Orthodox MS symptoms treatment

November 20th, 2007 | Posted in MS enigma

Orthodox medicine presently is using two drugs groups to possibly reduce MS symptoms:

Orthodox medicine, driven by very powerful multi-billion pharmaceutical industry, proposes some medicines for some multiple sclerosis symptoms treatment. Today’s reality – every drug available in medicine today carries a risk of side effects, including over the counter remedies.

No corticosteroid treatment is currently approved, however, those disease modifying therapies that reduce progression of Primary Progressive and Progressive/Relapsing Multiple Sclerosis MS may be beneficial.

Currently used multiple sclerosis drugs are immunomodulatory. This means the approved drugs used specifically in the treatment of multiple sclerosis have a direct effect on immune system and therefore their use carries the risk of compromising the body’ s ability to fight infection and may also interfere with the body’ s tumor surveillance mechanisms…

The main problem is – the mechanisms by which the drugs exert their influence on the course of multiple sclerosis exacerbations is unknown. By definition this makes them experimental.

There are lots of information about all approved for MS treatment drugs. However, possible (and existing) side effects (sometimes very dangerous) are not so well documented.

Corticosteroids

Corticosteroids are prescribed for literally hundreds of conditions, including multiple sclerosis.

Short-term treatment (3-5 days) with corticosteroids (like prednisone, methylprednisolone, dexamethasone, others) can aid during periods of acute relapse.

Corticosteroids work by possibly decreasing the intensity of the body’s defense system’s reaction to the myelin in the central nervous system.

Many of the side–effects of steroids are predictable. Not all side–effects occur in all patients. All are related to:

  • the amount of steroid a patient takes a day
  • the length of time the patient remains on the medication

Prednisone is a replacement for a naturally in a body synthetised steroid Hydrocortisone, which was replaced with Prednisone because of the only reason – it can not be patented! So presently instead of natural steroid hormone is used synthetic one, containing lots of danfgerous adverse effects. More about many healing aspects of Hydrocortisone and other natural hormones – in an article ‘Hormones and Chronic Disease, where David Brownstein, MD, states: “I have yet to see a patient with rheumatoid arthritis or scleroderma (or other autoimmune disorders) who has normal hormone levels”.

Benefits

  • To hasten recovery from acute attacks
  • To prevent damage to the blood-brain barrier.

Some reported side effects:

  • Sodium retention
  • Increased appetite
  • Increased fat deposits
  • Increased acid in your stomach
  • Increased sweating, especially at night
  • Increased hair growth
  • Acne on the face, back, and chest
  • Bone and muscle problems
  • Growth problems in children
  • Eye problems
  • Increased sugar in the blood
  • Increased sensitivity to the sun
  • Delayed wound healing
  • Decreased ability to fight infection
  • Thrush (Candida) growth in the mouth…

By the way, very interesting and truthful explanation how steroids are worsening the situation came from web site “Electroherbalism” chapter “Autoimmune Disorders“:

The normal prescription for inflammatory disorders are strong antiinflammatories like steroids. These can certainly decrease symptoms but since they are covering up the problem and doing nothing to treat it, make it worse in the long run. A more ridiculous prescription for treating a pathogen-induced illness is a drug which decreases immune function. Since there are less immune cells to “call to arms” there is less inflammation. I can think of no better way to allow a pathogen to overrun and destroy tissue more quickly.

I initially was treated with mega dozes of injectable methyl-prednisone (Solu Medrol) and my situation after such a treatment worsened significantly.

MS immunomodulatory drugs

Avonex

Interferon beta-1a, recombinant DNA produced synthetic of naturally occurring proteins.

Benefits

  • To lower incidence of disease resistance associated with this dosing regimen

Some reported side effects:

  • Anaphylaxis
  • Autoimmune Disorders
  • Depression and Suicide
  • Hepatic Injury and Hepatitis
  • Injection Site Necrosis …

Unknowns:

  • Safety and Efficacy
  • Drug Interactions
  • Carcinogenesis
  • Pregnancy and Fertility…

Betaseron (Betaferon)

Interferon beta-1b is a recombinant DNA produced synthetic of naturally occurring proteins. It is manufactured by bacterial fermentation.

Benefits

  • To decrease rate of relapse
  • To decrease development of new lesions
  • To delay progression of disability

Some reported side effects:

  • Adverse Events
  • Anaphylaxis
  • Autoimmune Disorders
  • Depression and Suicide
  • Hepatic Injury and Hepatitis
  • Psychiatric Disorders
  • Seizures
  • Thyroid…

Unknowns:

  • Safety and Efficacy
  • Drug Interactions
  • Carcinogenesis
  • Spontaneous Abortion…

Copaxone

Glatiramer acetate (formerly copolymer-1)

Benefits

  • To decrease rate of relapse
  • To moderately decrease development of new lesions
  • To probably delay progression of disability

Some reported side effects:

  • Adverse Events
  • Anaphylaxis
  • Autoimmune Disorders
  • Chest Pains
  • Depression and Suicide
  • Hepatic Injury and Hepatitis…

Unknowns:

  • Safety and Efficacy
  • Carcinogenesis
  • Drug Interactions
  • Impairment of Fertility…

Rebif

Interferon beta-1a – recombinant DNA produced synthetic of naturally occurring proteins.

Benefits

  • To decrease rate of relapse
  • To decrease development of new lesions
  • To delay progression of disability

Some reported side effects:

  • Anaphylaxis
  • Autoimmune Disorders
  • Depression and Suicide
  • Flu-like Symptoms
  • Hepatic Injury and Hepatitis
  • Pregnancy…

Unknowns:

  • Safety and Efficacy
  • Drug Interactions
  • Carcinogenesis
  • Impairment of Fertility
  • Nursing Mothers…

We know that all drugs used to treat multiple sclerosis

  1. are mainly experimental
  2. induce dangerous side effects
  3. are associated with dangerous uknowns

That means that every multiple sclerosis sufferer before treatment must balance carefully MS symptoms reduction against the potential for adverse side effects.

Final notes:

  • I have no personal experience with multiple sclerosis drugs. I think I am extremely lucky (I wasn’t treated with any of them), especially considering that I know MS sufferers who had to discontinue such a treatment because of terrible and dangerous adverse effects.
  • I am not interested in multiple sclerosis drugs at all. However, substantially more complete, well presented and documented information can be found in a website specifically designed for multiple sclerosis drugs.
  • My most important message to all MS-ers – multiple sclerosis can be cured or at least tempered with all-natural dietary supplements. More information here.

News from MS market ’07

November 16th, 2007 | Posted in MS enigma

The dynamic MS market continues to grow unabated; seven major market revenues increased 14.7% from 2005 to $4.6 billion in 2006. Growth is driven by the highly successful beta-interferon brands, Teva’s Copaxone (glatiramer acetate), and the recent relaunch of Tysabri; the first launch of a new MS treatment for six years >>>

<<< Despite the comparatively large MS population, the UK only accounted for 1.1% of the 7MM (major market) total in 2006. Datamonitor believes the UK has potential to be a much more profitable and attractive MS market. If treatment rates were on par with Germany, the UK market could have been worth $293m in 2006almost six times higher than the actual value.

In order to successfully position a new drug class in the market, future market players must have a clear and focused marketing strategy. With Copaxonelaunched in 1997Teva has set the benchmark, and by utilizing similar tactics, future MS players can successfully position novel therapies in the market >>>

Full article – Pharmaceutical Business Review

* * * * *

Honestly, I can not catch the point of this article.

No single word about MS sufferers, MS symptoms reducing or elimination, nothing…

They speak about market, profits and possibilities (strategies) to make even money money (smart strategies). MONEY!

No single word about their drugs – what they are supposed to treat, efficiency, reliability, side effects etc.

By the way – all so-called MS drugs are experimental. Again – pharmaceutical industry makes multi-billion USD business, performing experiments on humans. More information: MS Treatment Market will Reach $11.9 Billion by 2011.

Psychology behind the scenes is shortly described in article Advantages of MS ! ? !.

However, there are lots of folks who managed to stop and/or reverse their MS symptoms.

I reversed my MS symptoms in 1997. I am on a permanent MS remission since.

Most importantly – there are known some major MS causes and some highly effective natural side effects-free MS cures.

One more thing – Multiple Sclerosis has the same origins as all other autoimmune diseases.

Everybody MUST choose what is best to him or her.

All best -

Dr. Czes Kulvis